Seraseal
What is SeraSeal™
A new and innovative hemostatic agent that is designed to stop bleeding on contact, and within seconds for arterial hemorrhages. This patented single component system can tackle any bleeding situation with the potential to save many lives.
Hemorrhages are one of the most common causes of death worldwide
Have you wondered how many deaths occur every year because of uncontrolled bleeding? Did you know hemorrhage is the leading cause of death worldwide? Hemorrhages can be in the form of uncontrolled bleeding after an accident, or controlled bleeding, for example during surgery. Acute bleeding during trauma or surgical interventions often results in unforeseen complications or loss of lives.
Have you wondered how many deaths occur every year because of uncontrolled bleeding? Did you know hemorrhage is the leading cause of death worldwide? Hemorrhages can be in the form of uncontrolled bleeding after an accident, or controlled bleeding, for example during surgery. Acute bleeding during trauma or surgical interventions often results in unforeseen complications or loss of lives.
Coagulation factors IIa, VIIa, IXa and Xa
Coagulation factors IIa, VIIa, IXa, and Xa function in an ancillary way by helping the agar to cross-link with the blood platelets and fibrinogen, thus strengthening the gelatin barrier. Tissue thromboplastin from platelets, which has been activated by damaged cells, assists in forming a clot.
How To Use SeraSeal™
SeraSeal™ is indicated for the control/stopping of (arterial and venous) hemorrhages and parenchymatous organs, seepage bleeding, capillary bleeding, vascular anastomoses etc. occurring in invasive, semi-invasive, and non-invasive procedures. SeraSeal™ is particularly suitable for surgical interventions.
Proven Effectiveness
The effectiveness of SeraSeal™ has been demonstrated in several studies. Even in difficult to control hemorrhages in the gastrointestinal area, bleeding was completely stopped in 87% of patients through the use of SeraSeal™. SeraSeal™ has been demonstrated to minimise blood loss and the necessity for blood transfusions during corrective osteotomies in craniosynostosis surgery.
Seraseal™ supports the body’s own blood coagulation process, acts as a catalyst in the clot formation process, and stops bleeding within 10-30 seconds without the application of pressure. It contains agar, an inert polysaccharide/carbohydrate, and coregulation factors (IIa, VIIa, IXa, and Xa) derived from bovine plasma.
How SeraSeal™ Works
Benefits & Efficacy in Surgery
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Liver Transplant
Seraseal™ In Liver Transplant Surgery
Injuries can cause bleeding in the front (or anterior chamber) of the eye between the cornea and the iris. This part of the eye holds a clear liquid called aqueous humor.
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Cosmetic & Reconstructive Surgery
Seraseal™ In Cosmetic And Reconstructive Surgery
- Breast: augmentation, reconstruction, gynecomastia, lift
- Abdomen: abdominoplasty, liposuction
- Head, face, eyes: facelift, nasal surgery, lip augmentation, craniosynostosis
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Brain & Spine Surgery
Seraseal™ In Brain & Spine Surgery (Seraseal™ Vs Other Conventional Products)
Time to hemostasis is too long for venous bleeds (1-3 minutes), and arterial bleeds (5-10 minutes for small arteries)in conventional products
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Obstetrics & Gynaecology
Benefits Of Seraseal™ In Obstetrics & Gynaecology
During childbirth, Cesarean section (CS) surgeries, average blood loss has been observed as 500-1500 ml (1-3 units of blood).
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Gastrointestinal Surgery
Seraseal™ In Gastrointestinal Surgery
Patients with active gastrointestinal bleeding can hugely benefit from Seraseal™ application.
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Cardiology & Cardiac Surgery
Seraseal™ In Cardiac Sciences
Seraseal™ is a clear and colourless hemostatic agent with a specific gravity of 1.02, which does not obscure the wound.
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Dialysis
How Seraseal™ Will Benefit Patients On Dialysis
The use of Seraseal™ for the creation of a fistula, graft, or placement of a catheter for dialysis is highly recommended during surgery to control bleeding, rather than cauterization, for Seraseal™ achieves haemostasis without destroying the tissues.
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Orthopedics & Joint Replacement
Benefits Of Seraseal™ In Orthopedics And Joint Replacement
In a Total Knee Arthroplasty (TKA) there are 3 forms of blood loss: visible blood loss from the surgical field; wound drainage, and blood loss into the tissues (hidden bleeding).
All About SeraSeal™
World’s Only Primary Hemostatic Agent that Stops Hemorrhages in Seconds
Effectiveness
Stops major hemorrhages in seconds without the need for ANY of the traditional applications of pressure, elevation, tourniquets, or cauterization
Application
All surgical setups, hospital departments, emergency/trauma centers, medical and surgical ICUs, private practice, dentistry, Armed Forces and law enforcement Agencies
Hemostasis
Stops venous bleeds in 1-3 seconds, small artery bleeds in 5-10 seconds, medium artery in 15-30 seconds and large artery bleeds in less than 60 seconds
Delivery
Through syringe, spray, foam, scope, torcher, catheter, trauma dressing, battlefield dressing, surgical sponges, dental compresses, swab, and bandage strip
SeraSeal™ Advantages
The Blood Savior
Supports the patient’s own coagulation system
- Seals hemorrhages within seconds
- Suitable for use in invasive/semi-invasive and non-invasive procedures
- Promotes healing
Can be applied to all tissues, including the bone marrow
- No tissue damage due to cauterization
- Can undergo repetitive freeze-thaw cycles without loss of activity
- Can be used outside of the clinical setting
No preparation, can be used immediately
- Reduces surgical time up to 50% (in most cases) and blood loss by 90% in upto 40% surgical procedures
- Substantial cost savings through less surgical theatre time, fewer blood transfusions
- Less anesthesia medication, less pain medication, shorter ICU and hospital stay
About Dr. Leon Wortham
Dr. Leon Wortham is the Owner, President & CEO of Wortham Laboratories, Inc. (Tennessee), which Develops new products (diagnostic, medical devices, pharmaceuticals), improves existing products (SeraSeal™ has CE Certification). He has previously worked as consultant for biotech companies. As R & D Chemist at Medical Analysis Systems, Camarillo, CA, Dr. Leon developed new clinical products, wrote SOPs and Quality Assurance procedures, and Hexcel Corporation, Chatsworth, CA where he Developed polyurethanes for medical applications, NASA project, S Military missile system. At Bio-Vet Laboratories, Annapolis, MD, as CEO he formed a veterinarian reference laboratory, developed clinical controls and reagents.
