Doctors Doing Surgery
25 May, 2022

Blood loss is a significant complication of an extensive surgery like neurosurgery. Major blood loss during neurosurgery can lead to several complications, including life-threatening hemodynamic instabilities. But this does not mean that the patient has to lose his life because of blood loss, there are various ways blood loss can be minimized during neurosurgery, and using a hemostatic agent is one of them.

The magnitude of the blood loss varies from minimal to massive during neurosurgery. Excessive blood loss can pose a threat to the patient’s life, and blood transfusion may mean a higher rate of sepsis and a longer duration of hospital and ICU stay.

There are 5 major challenges/limitations of conventional hemostatic agents in neuro-spinal surgeries:

  • The time to hemostasis is too long for venous bleeds (1-3 minutes), and arterial bleeds (5-10 minutes for small arteries)in conventional products.
  • Current products obscure the wound site, making it difficult to see any hidden bleeds.
  • SeraSeal™ reduces blood loss by 90%, while the currently available products will not reduce blood loss.
  • Other products create a mass to stop the bleed, and that mass can lead to cranial pressure post-op SeraSeal™ will not create cranial pressure, because the clotting time is so fast the fibrin clot that forms is very small.

Current hemostatic agents are limited to only certain types of neuro-surgical procedures because other complex surgeries are known for heavy to severe bleeding, sensitive sites within the brain that would be vulnerable to cranial pressure from the size of fibrin glue, and fibrin glue has the inability to address certain tumors removal with a procedure

Some Neuro-surgical cases would be restricted, and ineffective would be:

  • Aneurysm
  • Arteriovenous malformation
  • Certain tumors
  • Extracranial-intracranial bypass
  • Peripheral nerve tumor & more

Existing hemostatic agents that are left behind at closing will be prone to the possibility of producing an immune response. SeraSeal™, on the other hand, will not produce an immune response because it is removed from the wound site within 1-2 minutes after hemostasis has occurred through irrigation/suction.

Hidden bleeds: Cranial cavity is hard to reach the injured bleeding site; SeraSeal™ being liquid can be applied in an approximate location to allow it to reach hidden bleed, which comes as a huge advantage to surgeons.

What are the benefits of SeraSeal™ in neurosurgery?

Brought to India by Swasth Kare, SeraSeal™ is the world’s first and only primary hemostatic agent that stops bleeding in seconds. It is superior in efficacy and safety to arrest bleeds over current hemostatic and tissue sealant products. SeraSeal™ can reduce surgical time by as much as upto 50% in some cases, and blood transfusion by upto 90%, resulting in substantial cost savings. In addition, SeraSeal™ has multiple delivery systems, and it can be delivered by a syringe, spray, foam, scope, trochar, catheter, trauma dressing, battlefield dressing, surgical sponges, dental compresses, swabs, and bandage strip.

These delivery systems substantially expand the hemostatic market to include hospitals, ER/trauma centers, medical and surgical ICUs/clinics, private practice, dentistry, veterinarian medicine, paramedics, military, law enforcement, and over-the-counter products in the form of first-aid for the home, business, recreational and sporting events.

All competitor hemostatic and tissue sealing products are adjunct products, used for only oozing blood loss. The time to arrest the bleed is in minutes, as compared to seconds with SeraSeal™. The efficacy of the competitor products, as well as having a single delivery system, limits them in many surgical applications.

Contact us to know more about this revolutionary hemostatic agent!

25 May, 2022

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